DRIVING: The Orlando area is serviced by numerous options.
Interstate service I-4 runs through the east coast of Florida to the west coast.
I-95 runs down the west coast where you can opt for numerous routes to Central Florida including I-4, SR 528 (also known as the beach line and is a toll road), Highway 5o and additional routes. You can also use I-95 from South West Florida and take I-4 to Central Florida.
I-75 services the Mideast and the best option from there is the Florida Turnpike (toll road) to reach Central Florida another alternative is Highway 27 but this route is much more complicated and time consuming. I-75 also services the West Coast of Florida and then take I-4 to Orlando.
The Florida Turnpike is the best option no matter where you are coming from anywhere in the center of the Florida.
No matter where you are coming from there’s an easy route for you!
Airports that service Orlando are Orlando International Airport and Sanford International Airport.
Orlando Discount carriers include Southwest, Air Tran, Jet Blue and Spirit Airlines.
The major carriers are all here although many have a small footprint in Orlando. Most of the major airlines will route you through a hub. My advice is to shop! If you desire to fly nonstop to Orlando prepare yourself to pay higher fares generally speaking. The discount carriers particularly have many non stops from big markets flying to Orlando. If you happen to live in a hub city you will probably have the most choices for nonstop service to Orlando. Remember to check all details of extra costs for everything from bags (some airlines do not even give you your first checked bag for free and Spirit Airlines charges both for bags and carry on bags)
My personal picks for airlines to Orlando based on my experience are Southwest, Air Tran and Jet Blue Airlines. Though depending on where you are coming from other airlines may be a better option for you. For example Delta hub cities offer more nonstop flights to Orlando and if they compete with discount carriers you can often get nonstop service for the cost of a one stop flight.
Rail Service is available from Amtrak and if you want to bring your car you can check out Auto Train for service for you and your car. These are the most expensive transportation to Orlando but it does have benefits that may be for you!
Bus Service to Orlando is available but unless you are close to Orlando or part of a group this would be my last choice.